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ISBN: HB: 9780226265827

University of Chicago Press

October 2016

288 pp.

22.8x15.2 cm

45 halftones

HB:
£40,00
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Microbes from Hell

At the close of the 1970s, the two-domain classification scheme long used by most biologists – prokaryotes versus eukaryotes – was upended by the discovery of an entirely new group of organisms: archaea. Initially thought to be bacteria, these single-celled microbes – many of which were first found in seemingly unlivable habitats like the volcanic hot springs of Yellowstone National Park – were in fact so different at molecular and genetic levels as to constitute a separate, third domain beside bacteria and eukaryotes. Their discovery sparked a conceptual revolution in our understanding of the evolution of life, and Patrick Forterre was – and still is – at the vanguard of this revolution. In "Microbes from Hell", one of the world's leading experts on archaea and hyperthermophiles, or organisms that have evolved to flourish in extreme temperatures, offers a colorful, engaging account of this taxonomic upheaval. Blending tales of his own search for thermophiles with discussions of both the physiological challenges thermophiles face and the unique adaptations they have evolved to live in high-temperature environments, Forterre illuminates our developing understanding of the relationship between archaea and the rest of Earth's organisms. From biotech applications to the latest discoveries in thermophile research, from microbiomes to the communities of organisms that dwell on deep-sea vents, Forterre's exploration of life-forms that seem to thrive at the mouth of hell provides a glimpse into the early days of Earth, offering deep insight into what life may have looked like in the extreme environments of our planet's dawn.

About the Author

Patrick Forterre, former head of the Microbiology Department at the Institut Pasteur, is presently professor at the Institut Pasteur and professor emeritus at the Universite Paris-Saclay, France.

Reviews

"This is history told by a scientist who helped to make it... His book walks the reader through his fascinating journey to understand how life evolved. Today, Forterre believes that viruses played a vital part. 'Microbes from Hell', in interweaving a scientific life with the grand discovery of the archaea, is a wonderful homage to this exciting field, which continues to challenge our view of life's origins" – Sonja-Verena Albers, University of Freiburg, Nature

"Scientists who deal in the history of life have never been quite sure what to do with viruses... Viruses, Forterre argues, bequeathed DNA to all living things. Trace the ancestry of your genes back far enough, in other words, and you bump into a virus. Other experts on the early evolution of life see Forterre's theory as bold and significant. But although they find much to agree with – particularly the importance of viruses to evolution – many also regard Forterre's ideas as controversial... Forterre himself is trying to fill that gap by studying viruses that live in heat-loving archaeans. Archaean viruses are proving to be particularly diverse and bizarre – such as lemon-shaped species that don't finish growing until they have left their host cell. Because viruses have such ancient roots, they preserve a remarkable range of biochemical tricks" – Carl Zimmer, Science